Kent Claypool

The University of Texas, M.D. Anderson Cancer Center, Science Park - Research Division, Department of Carcinogenesis; P.O. Box 389, 1808 Park Road 1C, Smithville, TX 78957 (512) 237-9427 lab, (512) 237-9589 fax

Education

1981 - 1986 The University of Texas at Austin (B.S., Chemistry )

  • Welch Foundation Fellowship in Organic Chemistry: Synthesis of surfactants for tertiary oil recovery research. Synthesis of deuterated cholesterol for human clinical studies.
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    1975 U.S. Army Signal School

  • Field General COMSEC Repair Course (31S30)
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    1974 U.S. Marine Corps

  • Basic Electronics Course
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    Professional Experience

    1989 - Present The University of Texas

  • Currently Cell and Tissue Analysis Facility Core Manager (Flow Cytometry & Confocal Microscopy): M.D. Anderson Cancer Center, Science Park - Research Division

  • Project Manager for Wyeth-Ayerst Clinical Study: Department of Pharmacology, U.T. Medical School - Houston Entitled: A Prospective, Double-Blind, Randomized, Placebo-Controlled Study of the Safety of a Two Component Conjugated Estrogens Formulation Compared with Premarin in Postmenopausal Women. (Molecular Biology - RT-PCR/ABI-PE 7700, DD-PCR/Genomyx, & Robotics - Beckman Biomek 2000)

  • Research & Methods Development: M.D. Anderson Cancer Center Departments: Neuro-Oncology (Molecular Biology); Molecular Pathology (Flow Cytometry & Protein Chemistry, IL-14); and Carcinogenesis (Flow Cytometry & Confocal Microscopy)

    • 1986 - 1989 Baylor College of Medicine

  • Established Laboratory and Conducted Prostate Cancer Research: Department of Urology
    •  (Analytical Chemistry - HPLC & Molecular Biology)

    1979 - 1981 The University of Texas

  • Sr. Biomedical Instrumentation Technician: Department of Biomedical Instrumentation, M.D. Anderson Cancer Center
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    1978 - 1979 Dresser Industries (Atlas Division)

  • QC/QA Repair of Failed Down-Hole Logging Computers
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    1977 - 1978 Texas Instruments

  • QC/QA Repair of Failed Silent 700 Data Teminals
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    Publications

    Ambrus, J.L, Pippen, J., Joseph, A., Xu, C., Blumethal, D., Tamayo, A., Claypool, K., McCourt, D., Srikiatchatochorn, A., and Ford, R.J. (1993) Identification of a cDNA for a Human High-Molecular-Weight B-Cell Growth Factor Proc. Natl. Acad. Sci. USA 90:13 p.6330-6334

    Ford, R., Tamayo, A., Martin, B., Niu, K., Claypool, K., Cabanillas, F., and Ambrus, J. (1995) Identification of B-Cell Growth Factors (Interleukin-14: High Molecular Weight-B-Cell Growth Factor) in Effusion Fluids from Patients with Aggressive B-Cell Lymphomas Blood 86:1 p.283-293

    Sundaresan, A., Claypool, K., Mehta, K., Lopez-Berestein, G., Cabanillas, F., and Ford, R.J. (1997) Retinoid-Mediated Inhibition of Cell Growth with Stimulation of Apoptosis in Aggressive B-Cell Lymphomas Cell Growth & Differentiation 8:10 p.1071-1082

    Yan, M., Kuang, X., Qiang, W., Shen, J., Claypool, K., Lynn, W.S., and Wong, P.K. (2002) Prevention of Thymic Lymphoma Development in Atm-/- Mice by Dexamethasone Cancer Res. 62:18 p. 5153-5157

    Patrawala, L., Calhoun, T., Schneider-Broussard, R., Zhou, J., Claypool, K., and Tang, D.G. (2005) Side Population is Enriched in Tumorigenic, Stem-Like Cancer Cells, whereas ABCG2+ and ABCG2- Cancer Cells are Similarly Tunmorigenic. Cancer Res. 65:14 p.1-13

    Patrawala, L., Calhoun, T., Schneider-Broussard, R., Li, H., Bhatia, B., Tang, S., Reilly, J.G., Chandra, D., Zhou, J., Claypool, K., Coghlan, L., and Tang, D.G. (2006) Highly Purified CD44+ Prostate Cancer Cells from Xenograft Human Tumors are Enriched in Tumorigenic and Metastatic Progenitor Cells Oncogene 25:12 p.1696-1708

    Li, H., Chen, X., Calhoun-Davis, T., Claypool, K., and Tang, D.G. (2008) PC3 Human Prostate Carcinoma Cell Holoclones Contain Self-renewing Tumor-Initiating Cells. Cancer Res. 68:6 p. 1820-1825

    Military Experience

    1974 - 1977 U.S. Marine Corps

  • Secure Communications Equipment Technician (MOS 2881)
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  • NSA - ENTNAC
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    "Some people wonder all their lives if they've made a difference. The Marines don't have that problem." - Ronald Reagan

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    Last Updated: 17-March-08

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