PDF Boulanger C-M, Liang C, Russell RS, Lin R, Bedford MT, Wainberg MA, Richard S. Methylation of TAT by PRMT6 regulates HIV-1 gene expression. Journal of Virology, 79: 124-131, 2005.

PDF Swiercz R, Person MD, Bedford MT. Ribosomal protein S2 is a substrate for mammalian protein arginine methyltransferase 3 (PRMT3). Biochem J, 386: 85-91, 2005.

PDF Covic M, Hassa PO, Saccani S, Buerki C, Meier NI, Lombardi C, Imhof R, Bedford MT, Natoli G, Hottiger MO. Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression. EMBO J, 24: 85-96, 2005.

PDF Bedford MT and Richard S. Arginine methylation: An emerging regulator of protein function. Molecular Cell, 18: 263-272, 2005.

PDF Ludes-Meyers JH, Kil H, Bednarek AK, Drake J, Bedford MT, Aldaz CM. WWOX binds the specific proline-rich ligand PPXY: Identification of interacting proteins. Oncogene, 23: 5049-5055, 2004.

PDF Cheng D, Yadav N, King RW, Swanson MS, Weinstein EJ, Bedford MT. Small molecule regulators of protein arginine methyltransferases. J Biol Chem, 279: 23892-23899, 2004.

PDF Kim J, Lee J, Yadav N, Wu Q, Carter C, Richard S, Richie E, Bedford MT. Loss of CARM1 results in hypomethylation of TARPP and deregulated early T cell development. J Biol Chem, 279: 25339-25344, 2004.

PDF Cote J, Boisvert FM, Boulanger MC, Bedford MT, Richard S. Sam68 is an in vivo substrate for protein arginine N-methyltransferase 1. Molecular Biology of the Cell, 14: 274-287, 2003.

PDF Yadav N, Lee J, Kim J, Shen J, Hu MC-T, Aldaz CM, Bedford MT. Specific protein methylation defects and gene expression perturbations in CARM1-deficient mice. PNAS, 100: 6464-6468, 2003.

PDF Sotgia F, Bonuccelli G, Bedford MT, Brancaccio A, Mayer U, Wilson MT, Campos-Gonzalez R, Brooks JW, Sudol M, Lisanti MP. Localization of phospho-beta-dystroglycan (pY892) to an intracellular vesicular compartment in cultured cells and skeletal muscle fibers in vivo. Biochemistry, 42: 7110-7123, 2003.

PDF Ludes-Meyers JH, Bednarek AK, Popescu N, Bedford MT, Aldaz CM. WWOX, the common chromosomal fragile site, FRA16D, cancer gene. Cytogenetics and Genome Research, 100: 101-110, 2003.

PDF Aasland R, Abrams C, Ampe C, Ball LJ, Bedford MT, Cesareni G, Gimona M, Hurley JH, Jarchau T, Lehto VP, Lemmon MA, Linding R, Mayer BJ, Nagai M, Sudol M, Walter U, Winder SJ. Normalization of nomenclature for peptide motifs as ligands of modular protein domains. FEBS Letters, 513: 141-144, 2002.

PDF Frankel A, Yadav N, Lee J, Branscombe TL, Clarke S, Bedford MT. The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity. J Biol Chem, 277: 3537-3543, 2002.

PDF Lee J and Bedford MT. PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays. EMBO Reports, 3: 268-273, 2002.

PDF Espejo A, Cote J, Bednarek A, Richard S, Bedford MT. A protein-domain microarray identifies novel protein-protein interactions. Biochem Jrnl, 367: 697-702, 2002.

PDF Liu MY, Cai CS, Espejo A, Bedford MT, Walker CL. 14-3-3 proteins interact with the tumor suppressor tuberin at AKT phosphorylation site(s). Cancer Research, 62: 6475-6480, 2002.

PDF Goldstrohm AC, Albrecht TR, Sune C, Bedford MT, Garcia-Blanco MA. The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1. MCB, 21:7617-7628, 2001.

PDF Sotgia F, Lee H, Bedford MT, Petrucci T, Sudol M, Lisanti MP. Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif, PPxY, recruits SH2 domain containing proteins. Biochemistry, 40: 14585-14592, 2001.

Bedford MT and Leder P. The FF domain: A novel motif that often accompanies WW domains. TIBS, 24: 253-290, 1999.

Rentschler S, Linn H, Deininger K, Bedford MT, Espanel X, Sudol M. The WW domain of dystrophin requires EF-hands region to interact with beta-dystroglycan. Biol Chem, 380: 431-442, 1999.

Bedford MT, Reed R, Leder P. WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: The proline glycine and methionine-rich motif. PNAS, 95: 10602-10607, 1998.

Bedford MT, Chan DC, Leder P. FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. EMBO J, 16: 2376-2383, 1997.

Deng X, Bedford MT, Li C, Xu X, Yang X, Dunmore J, Leder P. Fibroblast growth factor receptor-1 (FGFR1) is essential for normal neural tube and limb development. Developmental Biology, 185: 42-54, 1997.

Chan DC, Bedford MT, Leder P. Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J, 15: 1045-1054, 1996.

Abud HE, Skinner JA, McDonald FJ, Bedford MT, Lonai P, Heath JK. Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge. Developmental Genetics, 19: 51-65, 1996.

Bedford MT, Arman E, Orr-Urtreger A, Lonai P. Analysis of the Hoxd-3 Gene: Structure and localization of its sense and antisense transcripts. DNA Cell Biol, 14: 295-304, 1995.

Hecht D, Zimmerman N, Bedford MT, Avivi A, Yayon A. Identification of fibroblast growth factor 9 (FGF9) as a high affinity, heparin dependent ligand for FGF receptors 3 and 2 but not for FGF receptors 1 and 4. Growth Factors, 12: 223-233, 1995.

Orr-Urtreger A*, Bedford MT*, Burakova T, Arman E, Zimmer Y, Yayon A, Givol D, Lonai P. Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Developmental Biology, 158: 475-486, 1993. *First two authors contributed equally.

Orr-Urtreger A, Bedford MT, Do M-S, Eisenbach L, Lonai P. Developmental expression of the A receptor for the platelet derived growth factor, which is deleted in the embryonic lethal patch mutation. Development, 115: 289-303, 1992.

Bedford MT and van Helden PD. Analysis of allele-specific methylation. TIGS, 6: 140-141, 1990.