Cell & Tissue Analysis Facility Core
Significance and Description
Many current research projects at Science Park focus on the mechanisms by which environmental agents affect cellular survival, growth, differentiation and/or neoplastic transformation. Thus, it is imperative to evaluate the consequences imposed by environmental agents on the expression and stability of key proteins that influence these processes. Also of interest are the effects of carcinogens and other environmental agents on cell cycle progression in affected tissues.
The Cell and Tissue Analysis Facility Core includes flow cytometry and confocal microscopy services. The flow cytometry service provides investigators with the ability to quantify surface and/or cytoplasmic protein expression in a variety of cell types, analyze the fraction of apoptotic cells, evaluate cell cycle parameters and sort cells into purified subsets based on these and other criteria. Confocal microscopy complements the quantitative advantages of flow cytometry by localizing cells, organelles or other subcellular components that express particular surface or cytoplasmic proteins in tissue sections using high-resolution digital imaging.
StaffEllen Richie, Ph.D., Director
Pamela Whitney, B.S., Cell and Tissue Analysis Facility Manager