Histology & Tissue Processing Facility Core
Significance and Description
Histological processing of tissue samples, as well as related techniques such as histochemistry, immunohistochemistry, autoradiography, and in situ hybridization, have become indispensable tools for the study of cellular responses to different environmental stimuli. In addition, the more recent use of microdissected paraffin sections in molecular biology studies for the detection of mutations, polymorphisms, DNA methylation patterns, etc., have made these techniques an essential component of many research projects.
Many current and proposed research projects of investigators utilize animal models in which the end point is the histopathological assessment of tissue pathology (e.g., toxicity, cell proliferation, neoplasia). In addition, some research projects utilize human tissues that must be analyzed at the microscopic level. Many projects also generate and use transgenic mouse models that require extensive characterization of tissue phenotypes.
The overall objective of this Facility Core is to provide both routine histology processing, as well as more specialized histochemical and immunohistochemical techniques to investigators. This Core also provides technical assistance, training, and consultations in histological techniques, necropsies and histopathological interpretation for investigators. Special techniques (e.g., the dissection of organs that require special skills and anatomical knowledge) are routinely developed for investigators as the need arises.
Staff
Irma B. Gimenez-Conti, D.D.S., Ph.D.,
Director
Nancy Wick Otto, BS, HTL (ASCP) QIHC
Research Lab Manager
Jimi Lynn Brandon, MS, HT (ASCP)
Research Lab Coordinator
Amanda Young, HT (ASCP)
Senior Research Histology Technician
Heather Ferrell
Histology Laboratory Assistant
Paula Ritchie
Histology Laboratory Assistant
Contact Us
Phone: 512-237-9432